Causes Of Stevens-Johnson Syndrome

Stevens-Johnson Syndrome (SJS) is usually caused by a response to a medicine that has been taken. The response may happen within one week to two months of taking the medicine. SJS may also be caused by infection, vaccinations, or diseases involving your organs or whole body. The cause of SJS may be unknown, and SJS risk may be genetic.

The most common medicines that may cause SJS are:

• Antibiotics (used to treat infection)
• Anti-seizure medicines (used to treat convulsions).
• Non-steroidal anti-inflammatory medicine (used to treat swelling or fever)
• Penicillins, which are used to treat infections

SJS causes are broken into four different categories:

• Infections 
• Drug Reactions   
• Malignancies 
• Unknown Causes.

Underlying viral infections that have been associated with Stevens Johnson Syndrome include herpes simplex, AIDS, coxackie viral infections, influenza, hepatitis, mumps, mycoplasmal infections and others.
Bacterial infections include diphtheria, Brucellosis, mycobacteriae, mycoplasma pneumonia and typhoid. Fungal infections previously associated with SJS include coccidioidomycosis, dermatophytosis and histoplasmosis. Certain types of protozoal infections, including malaria and trichomoniasis, have also been reported. Although Stevens Johnson Syndrome is relatively rare in children, it has been associated with Epstein-Barr virus.

                  < Symptoms                          Diagnosis >

Read more »

What Causes Acne?

How Acne Develops  

Acne happens when sebaceous (oil) glands attached to the hair follicles are stimulated at the time of puberty by elevated levels of male hormones. Sebum (oil) is a natural substance which l
ubricates and protects the skin. Associated with increased oil production is a change in the manner in which the skin cells mature so that they are predisposed to clog the follicular openings or pores. The clogged hair follicle gradually enlarges, producing a bump. As the follicle enlarges, the wall may rupture, allowing irritating substances and normal skin bacteria access into the deeper layers of the skin, ultimately producing inflammation.

Inflammation near the skin's surface produces a pustule; deeper inflammation results in a papule (pimple); deeper still and it's a cyst. If the oil breaks though to the surface, the result is a "whitehead." If the oil accumulates melanin pigment or becomes oxidized, the oil changes from white to black, and the result is a "blackhead." Blackheads are therefore not dirt and do not reflect poor hygiene.

Here are some factors that don't usually play a role in acne:

• Heredity: With the exception of very severe acne, most people do not have the problem exactly as their parents did. Almost everyone has some acne at some point in their life.

• Food: Parents often tell teens to avoid pizza, chocolate, greasy and fried foods, and junk food. While these foods may not be good for overall health, they don't cause acne or make it worse. Although some recent studies have implicated milk and pure chocolate in aggravating acne, these findings are very far from established

• Dirt: As mentioned above, "blackheads" are oxidized oil, not dirt. Sweat does not cause acne, therefore, it is not necessary to shower instantly after exercise for fear that sweat will clog pores. On the other hand, excessive washing can dry and irritate the skin.

• Stress: Some people get so upset by their pimples that they pick at them and make them last longer. Stress, however, does not play much of a direct role in causing acne.

In occasional patients, the following may be contributing factors:

• Pressure: In some patients, pressure from helmets, chin straps, collars, suspenders, and the like can aggravate acne.

• Drugs: Some medications may cause or worsen acne, such as those containing iodides, bromides, or oral or injected steroids (either the medically prescribed prednisone [Deltasone, Orasone, Prednicen-M, Liquid Pred] or the steroids that bodybuilders or athletes take). Other drugs that can cause or aggravate acne are anticonvulsant medications and lithium (Eskalith, Lithobid), which is used to treat bipolar disorder. Most cases of acne, however, are not drug related.

• Occupations: In some jobs, exposure to industrial products like cutting oils may produce acne.

• Cosmetics: Some cosmetics and skin-care products are pore clogging ("comedogenic"). Of the many available brands of skin-care products, it is important to read the list of ingredients and choose those which have water listed first or second if you are concerned about acne. These "water-based" products are usually safe.

< Signs And Symptoms                                                                           Diagnosis >

Read more »